Effects of Ingestion of Hornet Larval Salivary Amino Acid Mixture on Metabolic Responses during Exercise

Koh Mizuno, Kastumi Asano, Takashi Abe, Koji Morishita

The purpose of this study was to examin the effects of oral ingestion of Hornet Larval Salivary Amino Acid Mixture (now called VAAM) on metabolic responses during exercise.

Four groups of healthy male subjects consisting of sedentaries (n=6, 25. 7+-4.1 yrs, VO2Max: 43.2+-4.9 ml/kg/min), endurance runners (n=6, 22.8+-1.9 yrs, VO2max: 60.5+-3.3 ml/kg/min), sprinters (n=6, 21.3+-0.5 yrs, VO2max: 541+-4.5 ml/kg/min) and soccer players (n=6, 23.0+-0.9 yrs, VO2max: 47.7+-5.4 ml/kg/min) cycled for 30 minutes at an intensity of ventilatory threshold after 30 minutes of ingestion of either placebo (bovine casein amino acid; BCA, 10g/70kg body weight) or VAAM (10g/70kg body weight) under conditions of fasting more than 12 hours since the previous night. Blood samples were drawn from the antecubital vein at rest and during exercise and analyzed for blood glucose, lactate, serum free fatty acids (FFA), ketone body, epinephrine, norepinephrine, and cortisol.

There was a significant effect of VAAM on the metabolic responses of the athletes. These athletes showed tendencies toward a decreasing heart rate, rate of perceived exertion and respiratory exchange ratio and toward an increasing serum FFA and ketone body during exercise. These results suggest that ingestion of VAAM may be effective in reducing physical stresses thus improving overall performance in subjects who train both aerobically and anaerobically.