Effects of ingestion of Vespa Amino Acid Mixture under postprandial conditions on blood ketone body concentrations during prolonged exercise in humans
SAITOH Shinichi, TSUCHITA Hiroshi, MUKAI Naoki, and ABE Takashi
The subjects had either 380ml of a VAAM drink or a control drink 90 min after lunch and 380 ml during exercise. The VAAM drink contained 10.8 g of amino acid mixture and 38 g of sucrose, and the control drink 48.8 g of sucrose in 760 ml. The exercise started 120 min after lunch.
The ingestion of a VAAM drink significantly increased the concentrations of both serum 3-hydroxybutyrate and acetoacetate pre- and post-exercise, and that of serum glycerol during recovery periods. In the separate experiment, the ingestion of a VAAM drink elevated the level of blood glucagon under the same postprandial conditions.
These findings suggest that an additive effect of exercise and VAAM ingestion might stimulate hepatic ketogenesis and consequently increase blood ketone body concentrations during exercise under postprandial conditions. Furthermore, fat oxidation is still activated during athletic exercise, despite high blood glucose levels (from food digestion).